Food industry readers will want to review the FDA's newly released "Strategic Priorities 2011-2015" document. 2011 and 2012 will be the critical years for the most sweeping changes in food regulation in more than 70 years. However, FDA is tasked with a greatly expanded scope of responsibilities in a period of sharp budget restrictions from Congress. Numerous hard decisions on priorities will mean that there will be postponments in the implementation of some programs envisioned in the Food Safety Modernization Act. We will follow these developments closely in the years ahead.